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Diagnostic parameters and reliability of four rapid immunochromatographic tests for dengue 4 BJID
Mata,Veronica Elizabeth; Passos,Sonia Regina Lambert; Santos,Maria Angelica Borges dos; Buonora,Sibelle Nogueira; de Andrade,Carlos Augusto Ferreira; Lima,Monique da Rocha Queiroz; Costa,Betina Moreira; Hökerberg,Yara Hahr Marques.
ABSTRACT Background: Although performance of rapid immunochromatographic tests (RITs) for dengue virus (DENV) serotypes 1, 2 and 3 is relatively settled, evidence on accuracy of RITs for DENV-4 are based on studies with small sample sizes and with discrepant results. Objectives: To assess accuracy and inter-observer agreement of RITs targeting dengue nonstructural protein-1 (NS1) antigen - Dengue NS1-Bioeasy™, Dengue NS1 Ag Strip-Bio-Rad™, IVB Dengue Ag NS1-Orangelife™ and Dengue NS1-K130-Bioclin™ in DENV-4 samples. Methods: Study sample (n = 324) included adults presenting at an emergency unit in Rio de Janeiro, Brazil, with fever of ≤72 h and two or more dengue symptoms. A serum sample from each patient was tested by each RIT. A positive...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue; Immunochromatographic tests; Sensitivity and specificity; Reproducibility of tests; Diagnosis.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100058
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